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The Sequence Opinion #774: Everything You Need to Know About Audio AI Frontier Models

Some history, major milestones and players in audio AI.

Dec 18, 2025
∙ Paid
Created using GPT-5.2

Audio has become one of the next major frontiers for artificial intelligence. Recent advances are empowering machines to hear, understand, and generate audio with a sophistication approaching human-like ability. From speech recognition and voice synthesis to music generation and environmental sound analysis, frontier AI models for audio are tackling challenges unique to sound. In this essay, we explore the state-of-the-art in audio AI: the key technical hurdles in training these models, how audio modeling differs from text and image domains, the major platforms and players driving progress (both open-source and commercial), and the debate between building generalist multimodal systems versus audio-specialized models. The goal is to provide a comprehensive, engaging overview of cutting-edge audio AI for a technically savvy audience.

Audio’s Unique Challenges and Opportunities

Audio data is fundamentally different from text or images, presenting unique challenges for AI models. Audio is a continuous time-series signal – essentially a waveform often sampled at tens of thousands of samples per second. This means even a few seconds of audio involve very long sequences of data points. Unlike text (which has discrete tokens like words) or images (2D grids of pixels), raw audio is high-frequency and high-dimension. Capturing meaningful structure in audio requires modeling both short-term patterns (like phonemes or musical notes that last only tens of milliseconds) and long-term structure (like phrases, sentences, or an entire melody that can span many seconds or minutes). This multi-scale structure is particularly evident in complex audio like music: from individual notes and timbres up to the composition of a whole song, with repeating motifs and long-range dependencies.

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